JNCCN features updates on the NCCN Clinical Practice Guidelines in Oncology®, (solicited) review articles elaborating on guideline recommendations, health services research, and case reports highlighting molecular insights in patient care.

JNCCN's vision is to further the mission of NCCN by serving as the primary resource for information on NCCN Clinical Practice Guidelines (NCCN Guidelines®), innovation in translational medicine, and on scientific studies related to oncology health services research, including quality care and value, bioethics, comparative and cost effectiveness, public policy, and interventional research on supportive care and survivorship.